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Meaning of acidophilus

  • a lactobacillus (Lactobacillus acidophilus) that is added especially to dairy items (such as yogurt and milk) or prepared as a dietary supplement, is part of the typical intestinal tract and vaginal plants, and is used therapeutically particularly to promote intestinal health
  • likewise: a preparation consisting of such bacteria [1]


There are numerous genera of bacteria that fall under the category of probiotics – Bacillus, Lactobacillus, Paenibacillus, Enterococcus, Aeromonas, Alteromonas, Arthrobacter, Bifidobacterium, Microbacterium, Clostridium, Phaeobacter, Pseudoalteromonas, Pseudomonas, Rhodosporidium, Roseobacter, Streptomyces and Vibrio. But the most typically utilized across human and animal applications is genus Lactobacillus.

Lactobacillus is a genus that consists of Gram-positive, rod-shaped germs that are most frequently understood for their function in carbohydrate fermentation and the capability to produce lactic acid as a result of this procedure. Lactobacillus types do not have the capability to form endospores like their cousin Bacillus. For this reason, they are seldom found as free-living germs. These microbes initially got appeal as cultures essential for producing fermented milk items, like cheese and yogurt, and as probiotic germs for human beings.

The gut microbiome in human beings and other animals has been gaining increasing attention in the last number of years due to its substantial result on health. A range of species of gut bacteria directly and indirectly impact early advancement, the ability to process particular foods, immune response, hormone balance, weight, state of mind, and a wide variety of other procedures in the body. As our understanding of probiotic organisms has actually increased, so has our use of these probiotics in areas outside the human health and milk market.

Today, these germs are also commonly utilized in farming and aquaculture and play an extremely important role in animal health and sustainable production of food. Aside from Bacillus, Lactobacillus types are the most studied and widely used probiotic bacteria generally due to their excellent efficiency in promoting natural digestion and immune paths in animals.

From Discovery to Today

Utilizing bacteria for health benefits has a long history– among the first reported cases goes back to the Roman historian Plinius in 76 B.C. [1], who advised making use of fermented milk as a remedy for gastroenteritis. Among the very first Lactobacilllus types that was discovered was L. acidophilus, which was isolated from the human digestive tract in 1900. It was first recognized as Bacillus acidophilus, however after the discovery of the Lactobacillus types and unique recognition approaches, its taxonomy was modified and the species relabelled to Lactobacillus acidophilus.

Studying the fermentation procedure for yogurt production, Bulgarian scientist Stamen Grigorov discovered Bacillus bulgaricus in 1905 (now known as Lactobacillus delbrueckii subsp. bulgaricus). Motivated by his research, Ilya Metchnikoff, Russian zoologist, bacteriologist and immunologist, released a paper 2 years later on in which he stated that one of the main factors for the longevity of Bulgarian farmers was because of their everyday intake of yogurt. He recommended that cultures present in Bulgarian yoghurt might have the ability to inhibit the aging procedure caused by putrefactive bacteria in the colon.

The genus Lactobacillus was formally discovered in 1921 by American bacteriologists E.B. Fred, W.H. Peterson, and J.A. Anderson. The genus was characterized by the capability to metabolize particular sugars and other carbon-based compounds. It was very tough to appropriately identify the exact species before PCR (Polymerase Domino Effect) was found in 1983, a lot of different Lactobacillus types were put under the exact same name. With the discovery of new gene sequencing strategies, an entire brand-new world of Lactobacillus species was found and their application ended up being more specialized and effective.

Lactobacillus acidophilus in aquaculture

Aside from increasing the threat of antibiotic-resistant bacteria, antibiotic application likewise diminishes the gut microbiota in aquaculture types.

The aquaculture market has actually significantly broadened throughout the last twenty years, and it is forecasted that it will continue to grow in the coming years. In order to fulfill the increasing demands of the marketplace, the aquaculture market has actually begun to count on high stocking densities and aggressive feed input. These practices often lead to a lot of accumulated waste, poor water quality, and increased tension levels in animals, creating an extremely beneficial environment for pathogens to spread rapidly. In order to prevent the incidence of diseases and huge financial losses that opt for them, aquaculture producers have used a number of methods, including (till recently) antibiotic usage. Many nations have recognized the unfavorable impacts of antibiotics and prohibited their use in aquaculture, and many others are following their footsteps.

However, the restriction of prescription antibiotics leaves a huge gap in the tool kit of aquaculture manufacturers, now in need of an alternative that will be at least as effective as prescription antibiotics without the negative effects.

For this reason, many scientists and aquaculture experts have actually relied on probiotics.

There are lots of genera of probiotic bacteria, and they consist of a variety of particular and non-specific types. Lactobacillus is among the most commonly represented genera in animal health applications because of the many helpful effects they have on animal production.

How do Lactobacillus types enhance the health of fish and crustaceans?

Similar to other probiotics, Lactobacillus species support useful impacts on aquaculture species in a number of methods, both straight and indirectly. The 6 primary functions of Lactobacillus types in aquaculture consist of:.

  • Stimulation of intestinal tract (GI) advancement – Lactobacillus germs can colonize the gut of fish and crustaceans at early phases of development (larval phase) and guarantee their appropriate growth by avoiding the establishment of potentially damaging germs. This is really important, as pathogen infections in larvae are typically destructive to their development and result in permanent damage, in addition to weakened immune system. Lactobacillus species also help nutrient absorption, increasing feed efficiency and accessibility of required aspects for the advancement of larvae and young fish and shellfishes.
  • Enhancement of digestive function and weight gain – Lactobacillus species increase utilization of carbon sources with the help of their digestive enzymes, which increase nutrient accessibility, in addition to feed to yield conversion. These germs also increase the tightness of digestive tract mucosa and promote the activity of gut wall cells, so they improve the natural processes within their host’s gut. This leads to much better feed utilization, increased development rates, survival rates and weight gain in fish and shrimps.
  • Stimulation of the host’s immune reaction – Probiotic bacteria like Lactobacillus were revealed to have a helpful impact on host’s immune system by increasing the total number of lymphocytes, in addition to activity of lysozymes and other enzymes important for immune defense. They can promote non-specific immune responses and increase activity of the host’s monocytes, macrophages, natural killer cells, and other agents that handle undesirable residents of the gut microbiome. For instance, L. rhamnosus has the ability to increase respiratory burst in rainbow trout, which implies that it assists the fish to rapidly launch reactive oxygen compounds like hydrogen peroxide and superoxide anion. These substances play a crucial function in cell signaling and defense versus pathogens.
  • Increasing reproduction – Reproductive capability of aquaculture species is heavily influenced by the quantity of available nutrients– fats, proteins, vitamins, fatty acids, and so on. These aspects are required for every part of the reproduction process, and appropriate advancement of larvae. Lactobacillus probiotics can increase the fecundity of fish by synthesizing a few of those essential elements we discussed (like vitamin B complex), ensuring better carbon source usage, and stimulating natural resistance of aquaculture species. For instance, researchers studied a probiotic which contains Lactobacillus acidophilus, L. casei, Bifidobacterium thermophilum, and Enterococcus faescium, and its effect on fecundity of female green swordtail. The outcomes were clear– the number of fecundated fish increased practically 50% in the group that received probiotics compared to the variety of fecundated fish in control (fish that weren’t treated with the probiotic item).
  • Protection from pathogenic bacteria – The occurrence of diseases is really high in extensive farming and triggers major economic losses. To fight this problem, numerous aquaculture manufacturers previously depended on antibiotics, but due to the excellent risk of antibiotic-resistant germs, their usage became significantly restricted in lots of nations. Probiotics reveal terrific possible to completely fill this space and offer a more sustainable way of getting high yields and producing healthy marine animals, without increasing the danger of microbial resistance to prescription antibiotics and hurting the environment.
  • GI is among the most common places in animal bodies for facility of pathogenic bacteria. Probiotics have the capability to colonize the gut quickly and therefore lower the area where pathogens can adhere and develop their nests. By using up area and nutrients from hazardous bacteria, Lactobacillus types can outcompete them and therefore avoid disease development. Applying probiotics with Lactobacillus types was revealed to regulate the gut microbiome and stimulate the activity of enzymes important for immune responses. Some Lactobacillus species can help increase resistance to particular pathogens, for example, L. plantarum increases illness resistance to Vibrio harveyi in Pacific white shrimps, while L. acidophilus increases defensive reactions of giant fresh river prawn against pathogenic Vibrio species.
  • Improving water quality – Water quality is one of the key factors for healthy and successful production in aquaculture. Build-up of natural waste, ammonia, nitrites and nitrates is a continuous issue, and a high concentration of these compounds in water can trigger fantastic damage to fish and crustaceans, and increase their death. Simply changing the contaminated water with fresh water can be expensive in some areas, and also have an unfavorable effect on the environment, thinking about that the waste water is often launched without processing into streams, rivers, and seas. This is why sustainable manufacturers opt for bioremediation, and probiotic bacteria are used to kick-start this process. These germs are live organisms that have the capability to produce enzymes and metabolize hazardous compounds, and as such can supply advantageous and long-lasting results on water quality and animal health. Aside from the well-known bioremediatory types like Bacillus, Nitrosomonas and Nitrobacter, certain Lactobacillus types like L. plantarum and L. casei likewise show the ability to minimize the amount of hazardous waste in the water and enhance growth of shrimps.

The majority of aquaculture probiotics are consisted of a blend of species to achieve the very best effects; as a result, Lactobacillus species are found in a combination with Bacillus, Enterococcus, Lactococcus, Nitrobacter and other probiotic bacteria. The mix of species and their individual quantity in the product depends upon the aquaculture types and preferred impacts. [2]


Below are 9 ways in which Lactobacillus acidophilus might benefit your health.

It May Help Reduce Cholesterol

High cholesterol levels might increase the risk of heart disease. This is especially true for “bad” LDL cholesterol.

Fortunately, research studies suggest that specific probiotics can help reduce cholesterol levels which L. acidophilus may be more effective than other types of probiotics.

Some of these studies have examined probiotics on their own, while others have actually used milk drinks fermented by probiotics.

One study found that taking L. acidophilus and another probiotic for 6 weeks significantly reduced total and LDL cholesterol, however likewise “good” HDL cholesterol.

A comparable six-week study discovered that L. acidophilus by itself had no result.

Nevertheless, there is proof that combining L. acidophilus with prebiotics, or indigestible carbohydrates that help great bacteria grow, can assist increase HDL cholesterol and lower blood sugar level.

This has been demonstrated in studies utilizing probiotics and prebiotics, both as supplements and in fermented milk beverages.

Furthermore, a number of other research studies have actually revealed that yogurt supplemented with L. acidophilus helped reduce cholesterol levels by as much as 7% more than regular yogurt.

This recommends that L. acidophilus– not another component in the yogurt– was responsible for the helpful effect.


acidophilus taken in on its own, in milk or yogurt or in combination with prebiotics might assist lower cholesterol.

It Might Avoid and Decrease Diarrhea

Diarrhea affects people for a number of reasons, including bacterial infections.

It can be hazardous if it lasts a long time, as it results in fluid loss and, in some cases, dehydration.

A variety of research studies have actually shown that probiotics like L. acidophilus might help prevent and decrease diarrhea that’s associated with numerous illness.

Proof on the capability of L. acidophilus to deal with severe diarrhea in children is blended. Some studies have revealed a beneficial impact, while others have revealed no effect.

One meta-analysis including more than 300 children discovered that L. acidophilus helped in reducing diarrhea, but just in hospitalized kids.

What’s more, when consumed in combination with another probiotic, L. acidophilus might help reduce diarrhea caused by radiotherapy in adult cancer patients.

Likewise, it might help in reducing diarrhea connected with antibiotics and a typical infection called Clostridium difficile, or C. diff.

Diarrhea is also common in people who take a trip to various countries and are exposed to brand-new foods and environments.

A review of 12 research studies found that probiotics work at avoiding traveler’s diarrhea and that Lactobacillus acidophilus, in combination with another probiotic, was most reliable at doing so (19Trusted Source).


When consumed in combination with other probiotics, L. acidophilus may assist prevent and deal with diarrhea.

It Can Improve Symptoms of Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) impacts approximately one in five individuals in particular nations. Its signs include stomach pain, bloating and uncommon bowel movements.

While little is understood about the cause of IBS, some research recommends it might be triggered by specific types of bacteria in the intestinal tracts.

For that reason, a variety of studies have analyzed whether probiotics can help improve its symptoms.

In a study in 60 people with practical bowel disorders consisting of IBS, taking a mix of L. acidophilus and another probiotic for one to 2 months improved bloating.

A similar study found that L. acidophilus alone likewise lowered abdominal discomfort in IBS clients.

On the other hand, a research study that analyzed a mix of L. acidophilus and other probiotics found that it had no result IBS signs.

This might be described by another study recommending that taking a low dosage of single-strain probiotics for a brief period may enhance IBS signs the most.

Specifically, the research study shows that the very best method to take probiotics for IBS is to utilize single-strain probiotics, instead of a mix, for less than eight weeks, along with a dosage of less than 10 billion colony-forming units (CFUs) daily.

However, it’s important to pick a probiotic supplement that has actually been scientifically shown to benefit IBS.


acidophilus probiotics may enhance symptoms of IBS, such as abdominal pain and bloating.

It Can Assist Treat and Prevent Vaginal Infections

Vaginosis and vulvovaginal candidiasis prevail kinds of vaginal infections.

There is good proof that L. acidophilus can help treat and avoid such infections.

Lactobacilli are usually the most common bacteria in the vaginal area. They produce lactic acid, which prevents the growth of other harmful bacteria.

Nevertheless, in cases of particular vaginal conditions, other types of bacteria start to outnumber lactobacilli.

A number of research studies have actually found taking L. acidophilus as a probiotic supplement can avoid and deal with vaginal infections by increasing lactobacilli in the vaginal area.

Nonetheless, other research studies have found no result.

Eating yogurt that contains L. acidophilus might likewise prevent vaginal infections. Yet, both of the studies that analyzed this were rather small and would require to be replicated on a larger scale prior to any conclusions could be made.


acidophilus as a probiotic supplement may be useful in preventing vaginal conditions, such as vaginosis and vulvovaginal candidiasis.

It Might Promote Weight-loss

The bacteria in your intestines assist control food digestion and a variety of other physical procedures.

Therefore, they affect your weight.

There is some evidence that probiotics may assist you reduce weight, especially when numerous types are consumed together. Nevertheless, the proof on L. acidophilus alone is uncertain.

A current research study that combined the outcomes of 17 human studies and over 60 animal research studies discovered that some lactobacilli types caused weight-loss, while others may have added to weight gain.

It suggested that L. acidophilus was among the species that led to weight gain. However, most of the studies were performed in farm animals, not people.

Additionally, some of these older studies utilized probiotics that were originally believed to be L. acidophilus, however have because been determined as different types.

For that reason, the proof on L. acidophilus impacting weight is uncertain, and more extensive research studies are required.


Probiotics might be effective for weight loss, however more research is needed to determine whether L. acidophilus, in particular, has a substantial impact on weight in people.

It Might Assist Prevent and Lower Cold and Influenza Manifestations

Healthy germs like L. acidophilus can boost the immune system and therefore help reduce the danger of viral infections.

In fact, some research studies have actually recommended that probiotics may avoid and improve symptoms of the cold.

A few of these studies examined how efficiently L. acidophilus treated colds in children.

In one research study in 326 kids, 6 months of daily L. acidophilus probiotics decreased fever by 53%, coughing by 41%, antibiotic usage by 68% and days absent from school by 32%.

The exact same research study discovered that integrating L. acidophilus with another probiotic was a lot more reliable.

A similar research study on L. acidophilus and another probiotic likewise found similar favorable results for reducing cold symptoms in kids.


acidophilus by itself and in mix with other probiotics might reduce cold symptoms, specifically in kids.

It May Assist Avoid and Minimize Allergic Reaction Symptoms

Allergic reactions are common and can trigger signs such as a runny nose or scratchy eyes.

Fortunately, some proof suggests that certain probiotics can decrease the signs of some allergies.

One research study showed that consuming a fermented milk drink including L. acidophilus improved symptoms of Japanese cedar pollen allergic reaction.

Likewise, taking L. acidophilus for 4 months decreased nasal swelling and other symptoms in kids with perennial hay fever, a disorder that causes hay fever-like signs throughout the year.

A bigger study in 47 children discovered similar results. It revealed that taking a combination of L. acidophilus and another probiotic reduced runny nose, nasal stopping and other signs of pollen allergy.

Interestingly, the probiotics decreased the quantity of an antibody called immunoglobulin A, which is associated with these allergic reactions, in the intestines.


acidophilus probiotics can lower the symptoms of specific allergies.

It Might Assist Avoid and Minimize Symptoms of Eczema

Eczema is a condition in which the skin becomes swollen, resulting in itchiness and pain. The most common type is called atopic dermatitis.

Proof recommends that probiotics can decrease the signs of this inflammatory condition in both adults and kids.

One study discovered that giving a mix of L. acidophilus and other probiotics to pregnant ladies and their babies throughout the very first three months of life minimized the occurrence of eczema by 22% by the time the infants reached one year of age.

A similar study discovered that L. acidophilus, in combination with standard medical treatment, substantially enhanced atopic dermatitis signs in children.

Nevertheless, not all studies have revealed favorable results. A big study in 231 newborn kids provided L. acidophilus for the first 6 months of life found no beneficial effect in cases of atopic dermatosis. In fact, it increased level of sensitivity to irritants.


Some research studies have actually revealed that L. acidophilus probiotics can help in reducing the occurrence and symptoms of eczema, while other studies show no benefit.

It benefits Your Gut Health

Your gut is lined with trillions of bacteria that play an essential function in your health.

Normally, lactobacilli are great for gut health.

They produce lactic acid, which might prevent damaging germs from colonizing the intestinal tracts. They likewise guarantee the lining of the intestines remains intact.

acidophilus can increase the amounts of other healthy bacteria in the gut, consisting of other lactobacilli and Bifidobacteria.

It can likewise increase levels of short-chain fatty acids, such as butyrate, which promote gut health.

Another study carefully took a look at the effects of L. acidophilus on the gut. It discovered that taking it as a probiotic increased the expression of genes in the intestinal tracts that are involved in immune response.

These outcomes suggest that L. acidophilus may support a healthy immune system.

A different study analyzed how the mix of L. acidophilus and a prebiotic affected human gut health.

It discovered that the combined supplement increased the quantities of lactobacilli and Bifidobacteria in the intestinal tracts, along with branched-chain fatty acids, which are a fundamental part of a healthy gut.


Acidophilus can support gut health by increasing the amounts of healthy bacteria in the intestinal tracts.

How to Enjoy one of the most from L. Acidophilus

  1. acidophilus is a regular germs in healthy intestinal tracts, however you can reap a number of health benefits by taking it as a supplement or consuming foods which contain it.
  2. acidophilus can be consumed in probiotic supplements, either on its own or in mix with other probiotics or prebiotics.

However, it’s likewise discovered in a variety of foods, especially fermented foods.

The very best food sources of L. acidophilus are:.

Yogurt: Yogurt is usually made from bacteria such as L. bulgaricus and S. thermophilus. Some yogurts likewise consist of L. acidophilus, but just those that list it in the active ingredients and state “live and active cultures.”.

Kefir: Kefir is made from “grains” of bacteria and yeast, which can be added to milk or water to produce a healthy fermented drink. The kinds of germs and yeast in kefir can vary, however it commonly consists of L. acidophilus, among others.

Miso: Miso is a paste stemming from Japan that is made by fermenting soybeans. Although the main microorganism in miso is a fungi called Aspergillus oryzae, miso can likewise contain many germs, including L. acidophilus.

Tempeh: Tempeh is another food made from fermented soybeans. It can contain a variety of various bacteria, including L. acidophilus.

Cheese: Different varieties of cheese are produced by utilizing different bacteria. L. acidophilus is not frequently used as a cheese starter culture, but a number of research studies have actually analyzed the effects of including it as a probiotic (54Trusted Source).

Sauerkraut: Sauerkraut is a fermented food made from cabbage. The majority of the germs in sauerkraut are Lactobacillus species, consisting of L. acidophilus (55Trusted Source).

Besides food, the best way to get L. acidophilus is directly through supplements.

A variety of L. acidophilus probiotic supplements are available, either by themselves or in mix with other probiotics. Aim for a probiotic with a minimum of one billion CFUs per serving.

If taking a probiotic, it’s typically best to do so with a meal, preferably breakfast.

If you are new to probiotics, try taking them once daily for a week or two and then examine how you feel before continuing.


acidophilus can be taken as a probiotic supplement, however it’s also discovered in high quantities in a number of fermented foods. [3]

How to utilize

People can quickly include L. acidophilus and other probiotics to their diet plan. A convenient and popular way of doing this is through yogurts and yogurt beverages, but some other fermented foods likewise contain L. acidophilus. Nevertheless, constantly examine the label to ensure the product does include L. acidophilus.

When taking L. acidophilus dietary supplements, select a credible brand name, and always follow the package instructions. A medical professional, pharmacist, or herbalist can also help with choosing the ideal L. acidophilus supplement. [4]

Dosage and Preparation

Acidophilus supplements are sold in a variety of types: capsules, tablets, beverages, pearls, powders, chewable wafers, liquids, and suppositories.

The common adult dose is 1 to 10 billion living organisms referred to as colony-forming units (CFUs), taken in approximately 4 divided doses. Follow the instructions on the packaging or speak to a healthcare provider about the suitable dose for you.

If offering L. acidophilus to a child, check with a pediatrician about a proper dosage or acquire a brand created for kids and follow the directions on the packaging.

Depending on the manufacturing procedures, you may discover some probiotics require refrigeration while others are shelf-stable. Make certain to keep probiotics as directed on the label and decrease contact with air. [5]

What are the potential negative effects of acidophilus?

Acidophilus is usually considered safe to utilize. However it does have some potential minor negative effects. These negative effects consist of:.

  • Mild upset stomach.
  • Diarrhea.
  • Constipation.
  • Gas and bloating.

If you develop signs of an infection such as fever or chills, stop taking acidophilus immediately. Contact your healthcare provider instantly for additional guidance.

Indications of an allergy may include:

  • Rash.
  • Itching.
  • Hives and swelling of your face, lips, tongue or throat.
  • Difficulty breathing.
  • Dizziness.

While uncommon, severe infections can occur. If you have any of the list below conditions, you must speak with your healthcare provider before taking acidophilus.

Central lines: Acidophilus has actually caused blood infections in individuals who have central lines. Central lines are long catheters (thin, versatile tubes) that are positioned in a large vein in your body.

Liver scarring: Acidophilus has triggered infections in individuals with cirrhosis.

Digestive system diseases: Acidophilus has caused infections in people with intestinal illness. These diseases consist of short bowel syndrome and inflammatory bowel disease.

Compromised body immune system: Acidophilus has actually triggered blood infections in people with crucial illnesses. This includes individuals with HIV/AIDS and individuals going through chemotherapy for cancer. This also consists of people who are taking medications to prevent rejection of an organ transplant.

Harmed heart valves: Acidophilus has caused infections in the lining of the heart chambers and heart valves. [6]

Special Safety Measures and Warnings

When taken by mouth: L. acidophilus is most likely safe. It’s been used securely together with other probiotics for approximately 9 months. Some people might experience gas or bloating, but it’s generally well-tolerated.

When applied to the vaginal area: L. acidophilus is most likely safe. It’s been utilized safely for approximately 12 weeks.

Pregnancy: L. acidophilus is potentially safe when taken by mouth during pregnancy. It’s been utilized securely together with other probiotics for 6 weeks, starting at 24-28 weeks of pregnancy.

Breast-feeding: There isn’t enough reliable info to understand if L. acidophilus is safe to use while breast-feeding. But there’s no factor to expect safety issues when used properly under medical supervision.

Kids: L. acidophilus is likely safe when taken by mouth properly in kids. It’s been used securely alone and together with other probiotics.

Compromised body immune system: Some probiotics have caused blood infections in a small number of people with weakened body immune systems. If you have a weakened immune system, talk with your healthcare provider before taking probiotics, including L. acidophilus.

Harmed heart valves: Some probiotics have triggered infections of the inner lining of the heart chambers and heart valve. This is incredibly rare, however people with broken heart valves ought to stop taking probiotics like Lactobacillus acidophilus prior to dental procedures or surgical procedures. [7]

Security score:

  • No security concerns despite wide usage. [8]


There are no recognized considerable interactions for acidophilus. [9]

The bottom line

Lactobacillus acidophilus is a types of probiotics that has actually been widely studied by itself and in mix with other probiotic types. Acidophilus has actually been shown to reduce bloating, assistance GI function, and support overall gut health. * The bright side? Specific premium probiotics developed with gut health specifically in mind, like probiotic+, combine several stress of probiotics, consisting of L. acidophilus, so you get whatever you require in one convenient pill. [10]


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